Biotinylated Human Tim-3/HAVCR2 , His -Avi TagTIM 3 is a member of the TIM family of immune regulating molecules. TIMs are type I transmembrane glycoproteins with one Ig like V type domain and a Ser Thr rich mucin stalk region. Within the ECD, human TIM 3 shares 58% aa sequence identity with mouse and rat TIM 3. TIM 3 is upregulated on several populations of activated myeloid cells (macrophage, monocyte, dendritic cell, microglia, mast cell) and T cells (Th1, CD8+, NK, Treg). Its binding to

mesencephalic astrocyte-derived neurotrophic factor

91306_Manual_Ver

01 EU per 1μg of the protein by the LAL method

EN20231122

which is calibrated against human IL-7 standard

Competitively bind Anti-Flag monoclonal antibodies

Supplier T*#Q32 and Q33* maintain stable signals for up to 1 h

36(2):e22128

and increased dUTP tolerance

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including eosinophils

Note: After incubation at 37 °C for 1 hour